Agenda

Day 1: April 5

7:45-5:00
04/05/2016

Fogarty International Center Global Brain Network Meeting
April 5-7, 2016
6001 Executive Boulevard
Neurosciences Center, National Institute of Health
Day 1
(April 5 Agenda)
https://meetings.fic.nih.gov/Home/Registration/13125
Global Brain Awards Listing: http://www.fic.nih.gov/Grants/Search/Pages/search-grants.aspx?program=globa1oa

7:45-8:30 
Registration
Coffee/Tea On Your Own

7:45-8:30 
Poster Set-up and Installation

8:30-8:40 
Introductory Remarks
Kathleen Michels, Program Director, Neurosciences Cluster/ Division of International Training and Research, FIC

8:40-8:50 
Director’s Welcoming Remarks
Roger Glass, Director of Fogarty International Center

8:50-9:25 
NIH Institute Remarks and Special Notices, and Hot Topics ( Zika virus, Ebola virus, and Alzheimer’s Disease)
Danuta Krotoski, National Institute of Child Health and Human Development  (NICHD)
Claudia Moy, National Institute of Neurological Disorders and Stroke  (NINDS)
May Wong, NeuroAIDS and Infectious Diseases (NINDS)
Beverly Pringle, National Institute of Mental Health (NIMH)
Jeymohan Joseph, Division of AIDS Research, National Institute of Mental Health
Dallas Anderson, National Institute of Aging (NIA)
Kimberly Gray, National Institute of Environmental Health Sciences (NIEHS)
Steve Gust, National Institute on Drug Abuse (NIDA)

Zika and other Neuro-Infections: NIH Notices and FOAs:
Nahida Chakhtoura, Maternal and Pediatric Infectious Diseases Branch, NICHD

9:25-10:15
Overview : “Brain Disorders across the Lifespan: Research to Achieve Nervous System Health
Worldwide” Nature Supplement
http://www.nature.com/nature/supplements/collections/npgpublications/brain-disorders/index.html

Moderator: Nalini Anand, Director, Center for Global Health Studies, FIC

Brain and other nervous system disorders across the lifespan- global challenges and opportunities
Donald Silberberg, Professor, Dept. of Neurology, University of Pennsylvania

Reducing neurodevelopmental disorders and disability through research and interventions
Michael Boivin, Professor, Psychiatry, Neurology and Ophthalmology, Michigan State University

A focus on adolescence to reduce neurological, mental health, and substance-abuse disability
Leslie Davidson, Professor, Department of Epidemiology and Pediatrics, Columbia University

Global research challenges and opportunities for mental health and substance-use disorders
Florence Baingana, Mental Health Lead, WHO Sierra Leone

A global perspective on the influence of environmental exposures on the nervous system
Desire Tshala-Katumbay, Associate Professor of Neurology, Oregon Health and Sciences University

Global neurotrauma research challenges and opportunities
Nancy Carney, Research Associate Prof, Dept. of Medical Informatics and Clinical Epidemiology

Global research priorities for infections that affect the nervous system
Chandy John,  Professor of Pediatrics, Microbiology, Immunology, and Medicine, Indiana University

Wrap-Up and questions to participants:
Kathy Michels, Program Director, Neuroscience Cluster, Div. of International Training and Research 

10:15-10:45  
BREAK AND POSTER SESSION

10:45-12:15

12:15-12:35 N
NEURO-INFECTIOUS DISEASES SESSION
Moderator: Chandy John

Special Talks:
Overview and updates on Ebola
Avindra Nath, NINDS Clinical Director, Section of Infections of the Nervous System

Zika Virus: What we know to date
Nahida Chakhtoura, Maternal and Pediatric Infectious Diseases Branch, NICHD

Discussion

GRANTEE TALKS:
Moderator: Chandy John

Chagas Disease Scan Study (R01, BRAZIL)
Jamary Oliveira-Filho, Associate Professor, Federal University of Bahia

Neurodevelopmental outcomes in severe malaria (UGANDA, R01)
Robert Opoka, Senior Lecturer, Dept. of Pediatrics and Child Health, Makerere University

12:35-1:30 
LUNCH  (On your own)

1:30-2:00 
Neuro-infections Grantee talks continued:
Moderator: Chandy John

EFECAB: Improving Pig Management to Prevent Epilepsy in BURKINA FASO (R01)
Hélène Carabin, Presidential Professor, University of Oklahoma Health Sciences Center

A New Focus of Epilepsy Associated with onchocerciasis in the DRC, CONGO (R21)
Dieudonné Mumba Ngoyi, Head of Dept. Parasitology, Institut National de Recherche Biomedicale Kinshasa, DRC CONGO
Jean-Claude Mwanza, Dept of Ophthalmology, UNC Chapel Hill & University of Kinshasa

Chemokines in Zambian children with cerebral malaria (R21, ZAMBIA)
Stins, Monique, Assistant Professor, Johns Hopkins

DISCUSSION
2:00-3:10 
HIV/NEURO-AIDS
Moderator: Ned Sacktor

Neurologic Sequelae of HIV Subtype A and D Infection and ART Rakai, UGANDA(Sacktor, R01)
Deanna Saylor, Clinical and Research Fellow, Neuro-Infectious Diseases, Johns Hopkins School of Medicine

Longitudinal Neuroimaging and Cognitive Study of HIV-Infected Children ( SOUTH AFRICA, R01)
Ernesta Meintjes, Research Chair in Brain Imaging, University of Capetown

Neuropathogenesis and Neuroinvasiveness of Subtype C Human Immunodeficiency Virus ( SOUTH AFRICA, R01)
For Yue Tso, Post-Doctoral Research Associate, Nebraska Center for Virology

DISCUSSION

HIV ASSOCIATED  ISSUES AND TREATMENTS

Efficacy of Adjunctive Sertraline for the Treatment of HIV-Associated Cryptococcal Meningitis (R01)
David Meya, Senior Lecturer, Infectious Diseases Institute, Kampala, Uganda

Cohort of HIV-Associated Seizures and Epilepsy in Zambia (PI: Birbeck)  (R21)
Izukanji Sikazwe, Deputy Chief Executive Officer, Center for Infectious Disease Research in Zambia

Treatment for depression and adherence in people living with HIV in Zimbabwe (R21)
Melanie Abas, Center for Global Mental Health, University College London

A Community-Based Evaluation of Interventions for Orphans and Vulnerable Children ( ZAMBIA, R01)
Elena Grigorenko, Professor of Psychology, University of Houston

DISCUSSION

3:10-3:40   
Break and Poster Session

3:40-4:15  
SUBSTANCE ABUSE/ ADDICTION
Moderator:  Jasmin Vassileva

Utility of machine-learning approaches to identify substance-specific behavioral markers for opiate and
stimulant dependence (Bulgaria) (R01)
Jasmin Vassileva, Associate Professor, Psychiatry, Virginia Commonwealth University

Mobile Motivational Interviewing Treatment for Alcohol Abuse in Kenya (R21)
Valerie Harder, Assistant Professor of Psychiatry and Pediatrics, University of Vermont

Combating craving with contingency management: neuroplasticity and methamphetamine abuse in South Africa (R21) (PI: Shoptaw)
Samantha Brooks, Senior Lecturer, Psychiatry, University of Cape Town

Khat Research Program: Neurobehavioral Impact of Long-Term Use (R21) (Yemen)
Mustafa Al’Absi, Professor, Department of Behavior Sciences,  University of Minnesota

DISCUSSION

4:15-5:05 
AGING AND NEURODEGENERATION
Moderator:  Gladys Maestre

Kerala-Einstein Study: Healthy lifestyle, vascular disease, and cognitive decline (India) (R01)
Verghese, Joe, Professor, Department of Medicine and Neurology, Albert Einstein College of Medicine

Gene-Environment Interaction in Cognition in Venezuelan Families (R01)
Gladys Maestre,  Professor of Psychiatry and Neurology, Columbia University

Successful Cognitive Aging and Cardiovascular Risk Factors in the Central Valley of Costa Rica (R21)
Jeremy Silverman, Professor, Department of Psychiatry, Mount Sinai

Lifestyle interventions for the prevention of cognitive decline in later life (Costa Rica)  (R21)
Monica Salazar-Villanea, Associate Professor and  Associate Director of Neurosciences, University of Costa Rica

Establishing Infrastructure for Prevention of Familial Alzheimer’s Disease in Mexico (R21)
John Ringman, Clinical Professor, Neurology, UCLA

Young Onset dementia in Latin America (R21) (Columbia, Mexico, Argentina, Peru)
Katya Rascovsky, Research Assistant Professor, Dept. of Neurology and Penn Frontotemporal Degeneration Center, University
of Pennsylvania

DISCUSSION

5:05-5:15 
Summary of Day One Presentations and Closing Remarks – POSTER  VIEWING UNTIL 5:30
Kathy Michels

6:30-8:00  
Dinner at Positano Ristorante Italiano (4948-4940 Fairmont Ave, Bethesda, MD 20814)


Day 2: April 6

7:30 am -5:00pm
04/06/2016 Global Brain Presentations and topical breakouts

April 5-7, 2016
6001 Executive Boulevard
Neurosciences Center, National Institute of Health
Day 2 (April 6 Agenda)
https://meetings.fic.nih.gov/Home/Registration/13125

7:30-8:15 
Registration  and Poster set up
Coffee/Tea On Your Own

8:15-8:45 
Grants Update
Farah Bader, Division of International Training and Research, Fogarty International Center

Implementation Science Opportunities
Laura Povlich, Program Officer, Fogarty International Center

8:45-9:15 
SPOTLIGHT ON  PERINATAL INFECTION AND HYDROCEPHALUS
Control of Neonatal Septisome and Hydrocephalus in Sub-Saharan Africa (Uganda) (NIH Pioneer Awardee)
Steve Schiff,  Director, Center for Neural Engineering, Pennsylvania State University

Neurocognitive Outcomes and changes in brain and cerebrospinal fluid volume after treatment
of post-infectious hydrocephalus (Uganda) (R01)
Benjamin Warf, Associate Professor of Neurosurgery, Harvard Medical School

DISCUSSION

9:15-9:50 
ENVIRONMENTAL EXPOSURES AND TOXINS
Moderator:  Desire Tshala-Katumbay

(Food) Cassava-Associated Neurodegeneration: Biomarkers, Cyanide, and Disease Susceptibility
at the Metagenomic/Epigenetic Interface (DRC-Congo) (R01)
Desire Tshala-Katumbay, Associate Professor of Neurology, Oregon Health and Sciences University,

Vulnerability of the Adolescent Brain to Organophosphorus Pesticides (Egypt) (R01)
Diane Rohlman, Associate Professor, University of Iowa

Prenatal and Early Childhood Biomass Smoke Exposure and Child Neurodevelopment (Sri Lanka; Sathiakumar) (R21)
Meghan Tipre, Post Doctorate, Department of Epidemiology, University of Alabama, Birmingham
DISCUSSION

9:50-10:15 
STROKE
Primary Prevention of Stroke in Children with Sickle Cell Diseases in Sub-Saharan Africa (Nigeria; DeBaun) (R01)
Brittany Covert, Project Manager, Vanderbilt University,

Reducing Stroke Burden in Uganda (R21)
Martha Sajatovic, Professor of Neurology and Psychiatry, Case Western University

DISCUSSION

10:15-11:00 
BREAK AND POSTER VIEWING

11:00-11:55 
NEURODEVELOPMENT
Moderator: Mohammad Rahbar

Health and Psychosocial Need: Children with Developmental Disorder in the Time of HIV (South Africa) (R01)
Leslie Davidson, Professor, Dept of Epidemiology and Pediatrics, Columbia University

Epidemiological Research on Autism in Jamaica- Phase 2 (ERAJ-2) (R01)
Mohammad Rahbar, Division Director, Professor- Clinical and  Translational Sciences, University of Texas
Health Science Center

Maternal Traumatic Stress and Child Development: Epigenetic Links (South Africa) (R21) (PI: Stein and Koenen)
Nastassja Koen, University of Cape Town

Epidemiology and etiology of hearing loss in newborns on the West Bank (R21)
James Coticchia, Director of Pediatric Otolaryngology, Wayne State University

Genetic Diagnosis of Neurodevelopmental Disorders with Exome Sequencing in India (R21)
Stephanie Bielas, Assistant Professor of Human Genetics, University of Michigan, Ann Arbor
Pre-Clinical and Patient Studies of Affective Disorders in Serbia  (R21)
Jelena Radulovic, Dunbar Professor in Bipolar Disease, Northwestern University

The effects of a home-based intervention conducted by college students for young children with intellectual
delays in Vietnam (R21)
Jin Shin, Associate Professor of Psychology, Hofstra University

DISCUSSION

12:00-1:00 
LUNCH

1:00-1:20 
Emerging Global Health Leaders (K43)
Christine Jessup, Program Officer, Fogarty International Center

1:20-1:50  
BRAIN INJURY AND NEUROREHABILITATION
Moderator:  Michael Boivin

A randomized controlled trial of the neuropsychological benefits of computerized cognitive rehabilitation
training in Ugandan children surviving severe malaria  (R01)
Michael Boivin,  Professor, Psychiatry, Neurology and Ophthalmology, Michigan State University

Traumatic Brain Injury Across the Lifespan in Uganda (R21)
Connie Hoe, Assistant Scientist,  Johns Hopkins Bloomberg School of Public Health

Capacity Building for Decompressive Craniotomy in Columbia (PI: Puyana) (R21)
Nancy Carney, Research Associate Prof, Dept. of Medical Informatics and Clinical Epidemiology

DISCUSSION

1:50-2:20 
Mental Health
Moderator:  Hader Mansour

Multi-pronged genetic studies of schizophrenia in an inbred population (Egypt)  (R01)
Hader Mansour, Assistant Professor of Psychiatry, University of Pittsburgh

Identification of psychosis risk trends in Africa (R21) (Kenya)
Daniel Mamah, Assistant Professor in Psychiatry, Washington University

Drug Discovery for Mental Disorders: Preclinical Studies of Peruvian Botanicals (R21) (Peru)
Carla Gallo, Professor, Department of Cell and Molecular Sciences and Laboratories of Research and Development, Universidad
Peruana Cayetano Heredia

DISCUSSION

2:20-3:00 
BREAK AND POSTER SESSION

3:00-4:15 
REGIONAL NATURE PAPER OVERVIEW
Donald Silberberg
http://www.nature.com/nature/journal/v527/n7578_supp_custom/full/nature16036.html

Research Capacity Building  Nature Paper Overview http://www.nature.com/nature/journal/v527/
n7578_supp_custom/full/nature16037.html
Kathleen Michels

Welcome Remarks from Division of International Relations (DIR)
Kenneth Bridbord, Acting Division Director, (DIR)

CONCURRENT SESSIONS (Choose one):
Regional  plus Capacity Building Discussion Sessions
(For each session, come prepared with questions/ Information  about and  to discuss, common themes,
capacity building, special issues, and hot topics from the regions/ countries)

Breakout 1) Middle East Region:
USG/NIH/FIC Updates: TBA 
Moderator: Mustafa Al’Absi

Breakout 2) Asia Region:
USG/NIH/FIC Updates: TBA
Moderator: Stephanie Bielas

Breakout 3) Latin American/Caribbean Region:
USG/NIH/FIC Updates: Kevin Bialy
Moderator: Jamary Oliveira-Filho

Breakout 4) Sub-Saharan Africa Region:
USG/NIH/FIC Updates: Kenneth Bridbord
Moderator; Jean-Claude Mwanza

Breakout 5) Nature Supplement Research Capacity Building Paper Follow-up:
Kathleen Michels/Donald Silberberg

4:15-4:45  
REGIONAL  and  CAPACITY BUILDING BREAK OUT DISCUSSION

4:45-5:00
Summary of Day 2 and Introduction to Day 3
Kathy Michels and Rachel Sturke

5:00-5:30
POSTER VIEWING


Day 3: April 7

8:30 am to 4:30 pm Implementation Science discussion, training, presentations
04/07/2016

Brain Implementation Science Learning Collaborative
Implementation Science Workshop
Overcoming Barriers to Implementation in Neuroscience
WORKSHOP AGENDA
April 7, 2016

Workshop Objective: To offer a brief implementation science training and facilitated
discussion on implementation science challenges related to brain and neuro-health in low- and middle-income countries

8:45AM  
Welcome and Introductions
Rachel Sturke, Deputy Director, Division of International Science Policy, Planning, and Evaluation, FIC
Desire Tshala-Katumbay, Associate Professor of Neurology, Oregon Health and Sciences University

9:00AM 
Update on Learning Collaborative Activities and Mandate for Day 3
Rachel Sturke

9:15AM 
Introduction to Implementation Science: Levels of Evidence, When to Implement, Evidence Synthesis, and Novel
David Chambers, Deputy Director for Implementation Science, NCI

10:15AM 
Panel: How Can Relevant Stakeholders Be Engaged and Kept Engaged: Perspectives from Different Stakeholders
Chair:  Beverly Pringle, Chief of the Global Mental Health Research Program, NIMH
Discussant:  Gladys Maestre, Professor of Psychiatry and Neurology at Columbia University

Panelists: Izukanji Sikazwe, Deputy Chief Executive Officer, Center for Infectious Disease Research in Zambia
Nadege Ngombe, Professor of Pharmaceutical Sciences, University of Kinshasa
Richard Idro, Pediatrician/Pediatric Neurologist, Mulago Hospital/Makerere University College of
Health Sciences in Uganda

11:00AM 
BREAK

11:15AM 
Panel: Adapting Evidence to the Local Context: Perspectives from Researchers,
Program Implementers, and Policymakers
Chair:  Belinda Sims, Health Science Administrator, NIDA
Discussant: David Chambers

Panelists: Florence Baingana, Mental Health Lead, WHO Sierra Leone
David Ndetei, Founding Director of the Africa Mental Health Foundation
Desire Tshala-Katumbay

12:00PM 
Discussion: Challenges in Identifying and Engaging Stakeholders and Identifying Implementation Gaps
Ian Campbell, Coordinator for Affirm Facilitation Associates and Consultant for the Salvation Army
USA Eastern Territory

12:30PM 
LUNCH

1:30PM 
Putting the Implementation Science Model to Work: Further Case Studies in Neuroscience
Chair:  Don Silberberg, Professor of Neurology, University of Pennsylvania 
Discussant: David Chambers

1:35PM  
Case 1 and Discussion
Chandy John, Professor of Pediatrics, Microbiology, Immunology, and Medicine, Indiana University
Robert Opoka, Pediatrician, Mulago Hospital/Makerere University College of Health Sciences in Uganda

2:00PM  
Case 2 and Discussion
Athanase Millogo, Neurologist, Central University Hospital Sourou Sanou in Burkina Faso
Hélène Carabin, Professor of Biostatistics and Epidemiology, University of Oklahoma Health Sciences Center

2:25PM  
Case 3 and Discussion
Lawrence Yang, Associate Professor of Epidemiology, Columbia University Medical Center

2:50PM  
BREAK

3:05PM 
Assessing Barriers in Implementation Science and Developing/Identifying Facilitators
for Overcoming Them
Greg Aarons, Co-Director of the Center for Organizational Research on Implementation and
Leadership and Professor in Department of Psychiatry, University of California, San Diego

3:50PM 
Scale, Spread, and Sustainability of Implementation/Needs Assessment
Sharon Straus, Director of the Knowledge Translation Program/Professor in Department of Medicine,
University of Toronto

4:35PM 
Learning Collaborative Next Steps

5:00PM 
Meeting Adjourns 

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